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ribostamycin sulfate

CAS No.: 53797-35-6      Formula: C17H36N4O14S

Weight: 552.55100

Synonyms: Riboflavine Sulfate; Ribostamycin sulfate salt;




Description

Ribostamycin is an aminoglycoside-aminocyclitol antibiotic isolated from a streptomycete, Streptomyces ribosidificus, originally identified in a soil sample from Tsu City of Mie Prefecture in Japan. It is made up of 3 ring subunits: 2-deoxystreptamine (DOS), neosamine C, and ribose. Ribostamycin, along with other aminoglycosides with the DOS subunit, is an important broad-spectrum antibiotic with important use against human immunodeficiency virus and is considered a critically important antimicrobial by the World Health Organization., Resistance against aminoglycoside antibiotics, such as ribostamycin, is a growing concern. The resistant bacteria contain enzymes that modify the structure through phosphorylation, adenylation, and acetylation and prevent the antibiotic from being able to interact with the bacterial ribosomal RNAs.

Basic Information
CAS No.:
53797-35-6
Synonyms:
Riboflavine Sulfate; Ribostamycin sulfate salt;
Formula:
C17H36N4O14S
Molecular Weight:
552.55100
PSA:
345.36000
LogP:
Properties
Appearance & Character:
Density:
1.6g/cm3
Melting Point:
175-180ºC
Boiling Point:
907.6ºC at 760 mmHg
Flash Point:
502.7ºC
Storage Conditions:
2-8ºC
Safety Info
Hazard Category Code:
R61
Security Instructions:
S22-S45-S53-S36-S37-S39
Dangerous Goods Sign:
T; Xi