(+|-)-EQUOL-94105-90-5-C15H14O3 -Chemindustry.com - The leading vertical market advertising source for the chemical world

CAS No.: 94105-90-5 Formula: C15H14O3

Weight: 242.27

Synonyms: 7,4'-HoMoisoflavane; NV; 07α; 3-(4-Hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol; 7-Hydroxy-3-(4-hydroxyphenyl)chroman; 4',7-Isoflavandiol; 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-chromen-7-ol;

Description

Equolisfirstisolatedandidentifiedfrompregnant-mares'urineandlaterfoundintheurineofthegoat,cow,henandsheep.Equol,unlikethesoyisoflavonesdaidzeinorgenistein,hasachiralcenterandthereforecanoccuras2distinctdiastereoisomers.S-equolistheexclusiveproductofhumanintestinalbacterialsynthesisfromsoyisoflavonesandbothenantiomersarebioavailable.S-equolhasahiChemicalbookghaffinityforestrogenreceptorbeta(Ki=0.73nM),whereasR-equolisrelativelyinactive.EquolcouldpromotetheproliferationanddifferentiationofratosteoblaststhroughactivatingtheER-PKCα-relatedsignalingpathway.Thealkalinephosphataseactivityalsoincreasessignificantlyinalloftheequoland17β-estradiol(E2)groups.Equolalsosignificantlyelevatestheosteocalcinlevels.

Basic Information

CAS No.:

94105-90-5

Synonyms:

7,4'-HoMoisoflavane; NV; 07α; 3-(4-Hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol; 7-Hydroxy-3-(4-hydroxyphenyl)chroman; 4',7-Isoflavandiol; 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-chromen-7-ol;

Formula:

C15H14O3

Molecular Weight:

242.27

PSA:

LogP:

Properties

Appearance & Character:

Density:

1.286±0.06 g/cm3(Predicted)

Melting Point:

158-160?C

Boiling Point:

441.7±45.0 °C(Predicted)

Flash Point:

Storage Conditions:

Inert atmosphere,Store in freezer, under -20°C

Safety Info

WGK Germany:

3