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Cholic acid

CAS No.: 81-25-4      Formula: C24H40O5

Weight: 408.57100

Synonyms: Cholan-24-oic acid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)-; (R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid;




Description

Cholic acid (also known as 3α,7α,12α-trihydroxy-5β-cholan-24-carboxylic acid, 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid) is bile The main component of acid, insoluble in water, soluble in ethanol and acetic acid, solid as white crystals, its salts are called cholates (English: cholates). Chole acid and chenodeoxycholic acid are the two major components of bile acids, which are produced by the liver metabolizing cholesterol. The concentrations of these two major bile acids in the human body are roughly equal. The derivatives of cholic acid are mainly generated by cholic acid-coenzyme A (cholyl-CoA), in which CoA can be exchanged with glycine or taurine to generate glycocholic acid or taurocholic acid.

Basic Information
CAS No.:
81-25-4
Synonyms:
Cholan-24-oic acid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)-; (R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid;
Formula:
C24H40O5
Molecular Weight:
408.57100
PSA:
97.99000
LogP:
3.44870
Properties
Appearance & Character:
White to Brown
Density:
1.184g/cm³
Melting Point:
200-201 °C(lit.)
Boiling Point:
545ºC
Flash Point:
321ºC
Storage Conditions:
Store at RT.
Safety Info
Signal Word:
Warning
Customs Code:
2942000000
WGK Germany:
2
Hazard Category Code:
R36/37/38
Security Instructions:
S24/25
Dangerous Goods Sign:
Xi