service@chemindustry.com
Sign in    |    Register

Polyethylene-polypropylene glycol

CAS No.: 9003-11-6      Formula: C5H10O2

Weight: 102.13200

Synonyms: Poloxamer; Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol);




Description

This product can increase the surface solubility of various drugs, such as salicylic acid, diazepam, indomethacin, metronidazole, etc., due to the formation of micelles by surfactants. As an absorption enhancer: on the one hand, this product slows down intestinal peristalsis, increases the retention time of the drug in the gastrointestinal tract and increases the absorption, thereby improving the bioavailability of oral preparations; on the other hand, this product has good compatibility with the skin, increasing the The skin permeability can promote the absorption of external medicines.

Basic Information
CAS No.:
9003-11-6
Synonyms:
Poloxamer; Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol);
Formula:
C5H10O2
Molecular Weight:
102.13200
PSA:
25.06000
LogP:
0.42170
Properties
Appearance & Character:
White crystal powder
Density:
1.095 g/mL at 25ºC
Melting Point:
60-50ºC
Boiling Point:
32.9ºC at 760 mmHg
Flash Point:
55.2ºC
Storage Conditions:
Safety Info
Hazard Category Code:
R21; R23/24/25; R25; R36/37/38
Security Instructions:
S23; S24/25; S45; S36/37/39; S26