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Trichlorfon

CAS No.: 52-68-6      Formula: C4H8Cl3O4P

Weight: 257.43700

Synonyms: Bilarcil; Chlorophos; (2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester,Metrifonate,Trichlorfon; 2,2,2-trichloro-1-dimethoxyphosphorylethanol; Metrifonate;


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Description

Metrifonate (INN) or trichlorfon (USAN) is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate (DDVP). It is used as an insecticide. It can be used to treat schistosomiasis caused by Schistoma haematobium, but is no longer commercially available. It has been proposed for use in treatment of Alzheimer's disease, but use for that purpose is not currently recommended.

Basic Information
CAS No.:
52-68-6
Synonyms:
Bilarcil; Chlorophos; (2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester,Metrifonate,Trichlorfon; 2,2,2-trichloro-1-dimethoxyphosphorylethanol; Metrifonate;
Formula:
C4H8Cl3O4P
Molecular Weight:
257.43700
PSA:
65.57000
LogP:
2.16090
Properties
Appearance & Character:
solid, Crystals
Density:
1.73
Melting Point:
77-81 °C
Boiling Point:
100°C
Flash Point:
Storage Conditions:
2-8°C
Safety Info
Customs Code:
29319090
WGK Germany:
3
Hazard Category Code:
22-43-50/53
Security Instructions:
24-37-60-61-2
Dangerous Goods Sign:
Xn, N