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Bacitracin

CAS No.: 1405-87-4      Formula: C66H103N17O16S

Weight: 1422.69000

Synonyms: baciguent; baci-jel; Baciguen; BACIDRIN; septa; Zutracin; Bacitracin; usafcb-7; ayfivin; ALTRACIN; Agfivin;


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Description

Bacitracin is a mixture of related cyclic peptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, first isolated in 1945. These peptides disrupt both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis. Bacitracin is primarily used as a topical preparation (as it can cause kidney damage when used internally). While the use of any antibiotic can contribute to antibiotic resistance, localized topical applications are less frequently implicated than their systemic counterparts. However, antibiotics such as bacitracin have been shown to act as dermatological irritants and may slow healing.

Basic Information
CAS No.:
1405-87-4
Synonyms:
baciguent; baci-jel; Baciguen; BACIDRIN; septa; Zutracin; Bacitracin; usafcb-7; ayfivin; ALTRACIN; Agfivin;
Formula:
C66H103N17O16S
Molecular Weight:
1422.69000
PSA:
556.17000
LogP:
3.72410
Properties
Appearance & Character:
Powder, white to faintly beige
Density:
1.43 g/cm³
Melting Point:
221-225°C
Boiling Point:
1750.1ºC at 760 mmHg
Flash Point:
1012.2ºC
Storage Conditions:
Keep in dark place,Inert atmosphere,2-8°C
Safety Info
Customs Code:
2941909000
WGK Germany:
2
Hazard Category Code:
R20/21/22
Security Instructions:
S22; S24/25; S45; S36
Dangerous Goods Sign:
Xn