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(+|-)-EQUOL

CAS No.: 94105-90-5      Formula: C15H14O3

Weight: 242.27

Synonyms: 7,4'-HoMoisoflavane; NV; 07α; 3-(4-Hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol; 7-Hydroxy-3-(4-hydroxyphenyl)chroman; 4',7-Isoflavandiol; 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-chromen-7-ol;


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Description

Equolisfirstisolatedandidentifiedfrompregnant-mares'urineandlaterfoundintheurineofthegoat,cow,henandsheep.Equol,unlikethesoyisoflavonesdaidzeinorgenistein,hasachiralcenterandthereforecanoccuras2distinctdiastereoisomers.S-equolistheexclusiveproductofhumanintestinalbacterialsynthesisfromsoyisoflavonesandbothenantiomersarebioavailable.S-equolhasahiChemicalbookghaffinityforestrogenreceptorbeta(Ki=0.73nM),whereasR-equolisrelativelyinactive.EquolcouldpromotetheproliferationanddifferentiationofratosteoblaststhroughactivatingtheER-PKCα-relatedsignalingpathway.Thealkalinephosphataseactivityalsoincreasessignificantlyinalloftheequoland17β-estradiol(E2)groups.Equolalsosignificantlyelevatestheosteocalcinlevels.

Basic Information
CAS No.:94105-90-5
Synonyms:7,4'-HoMoisoflavane; NV; 07α; 3-(4-Hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol; 7-Hydroxy-3-(4-hydroxyphenyl)chroman; 4',7-Isoflavandiol; 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-chromen-7-ol;
Formula:C15H14O3
Molecular Weight:242.27
PSA:
LogP:
Properties
Appearance & Character:
Density:1.286±0.06 g/cm3(Predicted)
Melting Point:158-160?C
Boiling Point:441.7±45.0 °C(Predicted)
Flash Point:
Storage Conditions:Inert atmosphere,Store in freezer, under -20°C
Safety Info
WGK Germany:3
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