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Vitamin E-TPGS

CAS No.: 9002-96-4      Formula: C39H66O8

Weight: 662.93700

Synonyms: Tocofersolan




Description

Tocofersolan (INN) or tocophersolan is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is polyethylene glycol derivative of α-tocopherol that enables water solubility. Tocofersolan is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fats due to disease. On 24 July 2009 the European Medicines Agency approved tocofersolan under the trade name Vedrop 50mg/ml oral solution for the treatment of vitamin E deficiency due to digestive malabsorption in paediatric patients suffering from congenital or hereditary chronic cholestasis, from birth (in term newborns) to 16 or 18 years of age (depending on the region). Tocofersolan is also used in cosmetics and pharmaceuticals as an antioxidant.

Basic Information
CAS No.:
9002-96-4
Synonyms:
Tocofersolan
Formula:
C39H66O8
Molecular Weight:
662.93700
PSA:
100.52000
LogP:
8.38890
Properties
Appearance & Character:
Transparent colorless solid
Density:
1.01g/cm3
Melting Point:
34-38ºC
Boiling Point:
662.7ºC at 760mmHg
Flash Point:
195.4ºC
Storage Conditions:
2-8ºC
Safety Info