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1-Methyl-L-4,5-dihydroorotic acid

CAS No.: 103365-69-1      Formula: C6H8N2O4

Weight: 172.13900

Synonyms: 4-Pyrimidinecarboxylicacid,hexahydro-1-methyl-2,6-dioxo-,(4S); 1-Methyl-L-4,5-dihydroorotic acid; (S)-3-methyldihydroorotic acid; (S)-1-METHYL-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIc acid; PYR140;




Description

1-methyl-L-4,5-dihydrolactic acid can be used as an intermediate in pharmaceutical synthesis. For example, it can be used to prepare tatirin, which is a pituitary hormone-releasing stimulant. It was successfully developed by Mitsubishi Chemicalbook Pharmaceutical Co., Ltd., Tanabe, Japan. Its trade name is Taltirelin, which belongs to the new chemical medicine category 3.1. At present, it is the most effective drug for improving the dyskinesia of patients with spinocerebellar degeneration.

Basic Information
CAS No.:
103365-69-1
Synonyms:
4-Pyrimidinecarboxylicacid,hexahydro-1-methyl-2,6-dioxo-,(4S); 1-Methyl-L-4,5-dihydroorotic acid; (S)-3-methyldihydroorotic acid; (S)-1-METHYL-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIc acid; PYR140;
Formula:
C6H8N2O4
Molecular Weight:
172.13900
PSA:
86.71000
LogP:
-0.72200
Properties
Appearance & Character:
White to Off-White
Density:
1.449 g/cm3
Melting Point:
212-214ºC
Boiling Point:
Flash Point:
Storage Conditions:
Inert atmosphere,Room Temperature
Safety Info
Dangerous Goods Sign:
Xn