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(1S,2S)-(+)-N-(4-Toluenesulfonyl)-1,2-Diphenylethylenediamine

CAS No.: 167316-27-0      Formula: C21H22N2O2S

Weight: 366.47700

Synonyms: (1S,2S)-N-(4-Toluenesulfonyl)-1,2-diphenylethylene-1,2-diamine; (S,S)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine; (1S,2S)-(+)-N-(4-Toluenesulfonyl)-1,2-diphenylethylenediamine; (S,S)-N-(2-Amino-1,2-diphenylethyl)-p-toluenesulfonamide; N-[(1S,2S)-2-amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide; (1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine;


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Description

(1S,2S)-N-(p-Toluenesulfonyl)-1,2-diphenylethanediamine is used as a catalyst in the synthesis of keramamine C, a carboline alkaloid that is isolated from the Okinawan sponge Amphimedon sp. (1S,2S)-N-(p-Toluenesulfonyl)-1,2-diphenylethanediamine is also used as a catalyst in the synthesis of Tolvaptan, a selective oral vasopressin V2-receptor agonist that is used to treat hyponatremia.

Basic Information
CAS No.:
167316-27-0
Synonyms:
(1S,2S)-N-(4-Toluenesulfonyl)-1,2-diphenylethylene-1,2-diamine; (S,S)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine; (1S,2S)-(+)-N-(4-Toluenesulfonyl)-1,2-diphenylethylenediamine; (S,S)-N-(2-Amino-1,2-diphenylethyl)-p-toluenesulfonamide; N-[(1S,2S)-2-amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide; (1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine;
Formula:
C21H22N2O2S
Molecular Weight:
366.47700
PSA:
80.57000
LogP:
5.88660
Properties
Appearance & Character:
crystal, White
Density:
1.224 g/cm³
Melting Point:
127-130ºC
Boiling Point:
537.3ºC at 760 mmHg
Flash Point:
278.8ºC
Storage Conditions:
Keep in dark place,Inert atmosphere,Room temperature
Safety Info
Customs Code:
29242990
WGK Germany:
3
Hazard Category Code:
36/37/38
Security Instructions:
26-36
Dangerous Goods Sign:
Xi