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2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride

CAS No.: 1185-53-1      Formula: C4H12ClNO3

Weight: 157.59600

Synonyms: Tris(hydroxymethyl)aminomethane hydrochloride; 2-Amino-2-(hydroxymethyl)-1,3-propanediol Hydrochloride; Tris(hydroxymethyl)aminometha; TRIS HCl,TRIS hydrochloride,Tris(hydroxymethyl)aminomethane hydrochloride; Tris Hydrochlorid


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Description

TRIS hydrochloride is a white crystalline powder that has a pKa of 8.08 at 25°C and pH range of 7.0 to 9.0 that coincides with the physiological pH of most living organisms because of which it is commonly used as a component of buffer solutions in biology, biochemistry and molecular biology applications. Tris salts are also used for crystallization of proteins at various pH values. Neither Tris base nor Tris hydrochloride by itself provide adequate buffering capacity. Generally the two need to be mixed together to provide a buffer with pH between 7 and 9 to provide adequate buffering.

Basic Information
CAS No.:
1185-53-1
Synonyms:
Tris(hydroxymethyl)aminomethane hydrochloride; 2-Amino-2-(hydroxymethyl)-1,3-propanediol Hydrochloride; Tris(hydroxymethyl)aminometha; TRIS HCl,TRIS hydrochloride,Tris(hydroxymethyl)aminomethane hydrochloride; Tris Hydrochlorid
Formula:
C4H12ClNO3
Molecular Weight:
157.59600
PSA:
86.71000
LogP:
-0.83690
Properties
Appearance & Character:
White
Density:
1.05 g/mL at 20 °C
Melting Point:
150-152 °C
Boiling Point:
357ºC at 760 mmHg
Flash Point:
169.7ºC
Storage Conditions:
Store at RT.
Safety Info
Customs Code:
2922199090
WGK Germany:
3
Hazard Category Code:
R36/37/38
Security Instructions:
S26-S36
Dangerous Goods Sign:
Xn