zolmitriptan-139264-17-8-C16H21N3O2 -Chemindustry.com - The leading vertical market advertising source for the chemical world

CAS No.: 139264-17-8 Formula: C16H21N3O2

Weight: 287.35700

Synonyms: (S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; Zolmitriptan; (4R)-4-[[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one;

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Description

Zolmitriptan is a selective serotonin receptor agonist of the 1B and 1D subtypes. It is a triptan, used in the acute treatment of migraine attacks with or without aura and cluster headaches. Zolmitriptan is marketed by AstraZeneca with the brand names Zomig, Zomigon (Argentina, Canada & Greece), AscoTop (Germany) and Zomigoro (France). In 2008, Zomig generated nearly $154 million in sales. AstraZeneca's U.S. patent on Zomig tablets expired on November 14, 2012, and its pediatric exclusivity extension expired on May 14, 2013. The patent in certain European countries has already expired too, and generic drug maker Actavis released a generic version in those countries, starting in March 2012.

Basic Information

CAS No.:

139264-17-8

Synonyms:

(S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; Zolmitriptan; (4R)-4-[[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one;

Formula:

C16H21N3O2

Molecular Weight:

287.35700

PSA:

57.36000

LogP:

2.25170

Properties

Appearance & Character:

Density:

1.217 g/cm3

Melting Point:

136-141ºC

Boiling Point:

563.3ºC at 760 mmHg

Flash Point:

294.5ºC

Storage Conditions:

Store in original container in a cool dark place.

Safety Info

Customs Code:

2934999090

Hazard Category Code:

R36/37/38

Security Instructions:

S26-S36

Dangerous Goods Sign:

Xi