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oxcarbazepine

CAS No.: 28721-07-5      Formula: C15H12N2O2

Weight: 252.26800

Synonyms: Oxcarbapezine; Ocarbazepine; OXACARBAZEPINE; Oxetol; 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide Oxacarbazepine; Oxcarbazepine; TRILEPTAL; 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide,Oxacarbazepine; Aurene; OXCARBAMAZEPINE; 10,11-Dihydro-10-oxo-5H-dibenzo[b,f]azepine-5-carboxamide; Oxecarb;


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Description

Oxcarbazepine is an anticonvulsant drug primarily used in the treatment of epilepsy. There is some evidence for oxcarbazepine as a mood-stabilizing agent and thus, it can be used as add-on therapy for bipolar disorder in patients that have failed or are unable to tolerate approved treatments. Common side effects include nausea, vomiting, dizziness, drowsiness, headache, double vision and trouble with walking. Although not common, anaphylaxis may occur. Due to its structural similarities to carbamazepine there is approximately a 25-30% chance of cross-reactivity between the two medications. Oxcarbazepine is marketed as Trileptal by Novartis and available in some countries as a generic drug. There is also an extended-release formation marketed as Oxtellar XR by Supernus Pharmaceuticals.

Basic Information
CAS No.:
28721-07-5
Synonyms:
Oxcarbapezine; Ocarbazepine; OXACARBAZEPINE; Oxetol; 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide Oxacarbazepine; Oxcarbazepine; TRILEPTAL; 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide,Oxacarbazepine; Aurene; OXCARBAMAZEPINE; 10,11-Dihydro-10-oxo-5H-dibenzo[b,f]azepine-5-carboxamide; Oxecarb;
Formula:
C15H12N2O2
Molecular Weight:
252.26800
PSA:
63.40000
LogP:
3.40750
Properties
Appearance & Character:
White to off-white crystalline powder
Density:
1.329g/cm3
Melting Point:
215-216°C
Boiling Point:
457ºC
Flash Point:
Storage Conditions:
Safety Info
Symbol:
GHS07
Signal Word:
Warning
Hazard Statement:
H302
Customs Code:
2933990090
WGK Germany:
3