service@chemindustry.com
Sign in    |    Register

donepezil

CAS No.: 120014-06-4      Formula: C24H29NO3

Weight: 379.49200

Synonyms: n-1-one; Donezepil; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Donepezil hydrochloride monohydrate; Donepezil Base; 2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; 5,6-Dimethoxy-2,3-dihydro-1H-inden-1-one; DONEPEZIL;


Search products supplier Encyclopedia

Description

Donepezil, marketed under the trade name Aricept, is a medication used in the palliative treatment of Alzheimer's disease. Donepezil is used to improve cognition and behavior of people with Alzheimer's, but does not slow the progression of or cure the disease. Common side effects include loss of appetite, gastrointestinal upset, diarrhea, difficulty sleeping, vomiting, or muscle cramping. It was developed by Eisai and Pfizer and is sold as a generic by multiple suppliers. Donepezil acts as a centrally acting reversible acetylcholinesterase inhibitor.

Basic Information
CAS No.:
120014-06-4
Synonyms:
n-1-one; Donezepil; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Donepezil hydrochloride monohydrate; Donepezil Base; 2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; 5,6-Dimethoxy-2,3-dihydro-1H-inden-1-one; DONEPEZIL;
Formula:
C24H29NO3
Molecular Weight:
379.49200
PSA:
38.77000
LogP:
4.29900
Properties
Appearance & Character:
Density:
1.141g/cm3
Melting Point:
207ºC
Boiling Point:
527.9ºC at 760mmHg
Flash Point:
273.1ºC
Storage Conditions:
Safety Info
Hazard Category Code:
R36/37/38
Security Instructions:
S26; S36
Dangerous Goods Sign:
Xi