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2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

CAS No.: 6197-30-4      Formula: C24H27NO2

Weight: 361.47700

Synonyms: Octocrilene


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Description

Octocrylene is an organic compound used as an ingredient in sunscreens and cosmetics. It is an ester formed by the condensation of a diphenylcyanoacrylate with 2-ethylhexanol. It is a viscous, oily liquid that is clear and colorless. The extended conjugation of the acrylate portion of the molecule absorbs UVB and short-wave UVA (ultraviolet) rays with wavelengths from 280 to 320nm, protecting the skin from direct DNA damage. The ethylhexanol portion is a fatty alcohol, adding emollient and oil-like (water resistant) properties. This organic compound can penetrate into the skin where it acts as a photosensitizer. This results in an increased production of free radicals under illumination. Free radicals are known to induce indirect DNA damage, and an increased concentration of free radicals might have contributed to the increased incidence of malignant melanoma in sunscreen-users compared to non-users (see Epidemiology of malignant melanoma)[weaselwords]. The only evidence gathered to date of a relationship between sunscreen use and malignant melanoma is correlational, but has not established a causal relationship.

Basic Information
CAS No.:
6197-30-4
Synonyms:
Octocrilene
Formula:
C24H27NO2
Molecular Weight:
361.47700
PSA:
50.09000
LogP:
5.77168
Properties
Appearance & Character:
Transparent and colorless viscous liquids
Density:
1.051 g/mL at 25 °C(lit.)
Melting Point:
−10 °C(lit.)
Boiling Point:
218 °C1.5 mm Hg(lit.)
Flash Point:
>230 °F
Storage Conditions:
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Safety Info
Customs Code:
2916129000
WGK Germany:
1