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Hydrocortisone

CAS No.: 50-23-7      Formula: C21H30O5

Weight: 362.46

Synonyms: Hydrocortisone, Chromatographic Standard; cortisol; 11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione; 11beta,17alpha,21-Trihydroxypregn-4-ene-3,20-dione; Hydrocortisone Base; 11,17,21-trihydroxypregn-4-ene-3,20-dione; (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione; 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one HYDROCORTISONE MICRONIZED; 11,17a,21-Trihydroxy-4-pragnene-3,20-dione;


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Description

Hydrocortisone (HC), also known as cortisol and cortisol, is an important adrenal glucocorticoid whose chemical name is 11β, 17α, 21-trihydroxypregn-4-ene -3,20-dione, its pharmacological action is through diffusion on target cells, binding to its receptors to form a steroid-receptor complex Chemicalbook, the activated steroid-receptor complex acts as an activator of gene transcription, and The dimer form binds to specific sequence chains on DNA, regulates gene transcription, increases mRNA production, and uses this as a template to synthesize corresponding proteins, which achieve the physiological and pharmacological effects of steroid hormones in target cells; HC It can affect glucose metabolism and has anti-inflammatory, anti-viral, anti-shock and anti-allergic effects.

Basic Information
CAS No.:
50-23-7
Synonyms:
Hydrocortisone, Chromatographic Standard; cortisol; 11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione; 11beta,17alpha,21-Trihydroxypregn-4-ene-3,20-dione; Hydrocortisone Base; 11,17,21-trihydroxypregn-4-ene-3,20-dione; (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione; 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one HYDROCORTISONE MICRONIZED; 11,17a,21-Trihydroxy-4-pragnene-3,20-dione;
Formula:
C21H30O5
Molecular Weight:
362.46
PSA:
LogP:
Properties
Appearance & Character:
White
Density:
1.28g/cm³
Melting Point:
211-214 °C(lit.)
Boiling Point:
566.4°C at 760 mmHg
Flash Point:
310.4°C
Storage Conditions:
-20°C
Safety Info
Customs Code:
29372100
WGK Germany:
3
Hazard Category Code:
62-63
Security Instructions:
36/37
Dangerous Goods Sign:
Xn