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4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol

CAS No.: 147118-36-3      Formula: C16H20FN3O3S

Weight: 353.41200

Synonyms: N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide; 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol;


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Description

4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-methanol is a new generation of Statin blood lipid-lowering drugs, which belong to HMG-CoA reductase inhibitors, can reduce elevated low-density cholesterol, total cholesterol, triglyceride and apoenzyme-based protein ChemicalbookB concentrations, while increasing high-density cholesterol concentrations. It can be used for the comprehensive treatment of primary hypercholesterolemia, mixed lipodystrophy and homozygous familial hypercholesterolemia. Compared with other statin hypolipidemic drugs, rosuvastatin has the advantages of definite curative effect, convenient and safe use, and less side effects, so it is called "super statin".

Basic Information
CAS No.:
147118-36-3
Synonyms:
N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide; 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol;
Formula:
C16H20FN3O3S
Molecular Weight:
353.41200
PSA:
91.77000
LogP:
3.37500
Properties
Appearance & Character:
White to Light Yellow
Density:
1.317 g/cm³
Melting Point:
137-140°C
Boiling Point:
538.273ºC at 760 mmHg
Flash Point:
Storage Conditions:
Sealed in dry,Room Temperature
Safety Info
Customs Code:
2935009090