Sacubitril-149709-62-6-C24H29NO5 -Chemindustry.com - The leading vertical market advertising source for the chemical world

CAS No.: 149709-62-6 Formula: C24H29NO5

Weight: 411.49100

Synonyms: ENTRESTO (Trade name, with Valsartan Sodium); 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; AHU-377; 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid;

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Description

Sacubitril (INN developmental code name AHU-377) is an antihypertensive drug used in combination with valsartan. The combination drug valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name Entresto, is a treatment for heart failure. It was approved under the FDA's priority review process for use in heart failure on July 7, 2015.

Basic Information

CAS No.:

149709-62-6

Synonyms:

ENTRESTO (Trade name, with Valsartan Sodium); 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; AHU-377; 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid;

Formula:

C24H29NO5

Molecular Weight:

411.49100

PSA:

92.70000

LogP:

4.22590

Properties

Appearance & Character:

Density:

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Boiling Point:

Flash Point:

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Safety Info